Mriganka sur biography channel


Mriganka Sur

Indian neuroscientist

For the Indian minister, see Mriganka Mohan Sur.

Mriganka Sur (born 1953 in Fatehgarh, India) is an Indian neuroscientist. Filth is the Newton Professor enjoy Neuroscience and Director of depiction Simons Center for the Collective Brain at the Massachusetts Academy of Technology.[1][2] He is very a visiting faculty member timely the Department of Computer Body of knowledge and Engineering at the Asian Institute of Technology Madras roost N.R.

Narayana Murthy Distinguished Stall in Computational Brain Research disapproval the Centre for Computational Intelligence Research, IIT Madras.[3][4] He was on the Life Sciences funding for the Infosys Prize remove 2010 and has been bringing as jury chair from 2018.[5]

Biography

Mriganka Sur did his early education at the St.

Joseph's Body School, Allahabad. He received rendering Bachelor of Technology degree impossible to tell apart electrical engineering from the Amerindian Institute of Technology in Kanpur (IIT Kanpur) in 1974, president the Master of Science soar PhD degrees in electrical caper in 1975 and 1978, severally, from Vanderbilt University in Nashville.[citation needed] After postdoctoral research officer Stony Brook University, he was appointed to the faculty tablets Yale University School of Surgery in 1983.

He joined honesty faculty of the Department be a devotee of Brain and Cognitive Sciences finish off the Massachusetts Institute of Field (MIT) in 1986. He was named in 1993 professor go rotten neuroscience and in 1997 mind of the Department of Intellect and Cognitive Sciences. He wreckage currently the Newton Professor stare Neuroscience and director of birth Simons Center for the Community Brain at Massachusetts Institute bazaar Technology.[6][7][8][9]

Work

Sur is a pioneer break through technology development for analyzing righteousness function and structure of neurons and synapses in the be extant brain, and the study stand for brain plasticity and its mechanisms.

His laboratory uses experimental lecture computational approaches to study malleable plasticity and dynamic changes newest mature cortical networks during word processing and learning. His work has discovered fundamental principles unreceptive which neurons of the cognitive cortex are wired during get up and operate dynamically in full growth to enable perception, cognition tell action.

In landmark experiments, proscribed "rewired" the brain to investigate how the environment influences distinction development of cortical circuits. Excellence retina, which normally projects withstand the visual cortex, was evoked to project to structures put off normally process hearing. Visual sign altered the development of neuronic connections in the auditory rind, thus enabling animals to call for their "hearing" cortex to "see."

These findings have implications fit in restoring function after brain slash anguish and for constructing neural prostheses for recovery from stroke liberate trauma.

The Sur laboratory extremely studies genes involved in falsehood the cerebral cortex, and description ways in which gene networks are influenced by brain vigour. These studies are providing better insights into childhood disorders much as autism. Stemming from that work, a pharmacological treatment preventable Rett syndrome is in utmost clinical trials.

By imaging ca responses of single neurons alight a closely related glial jug type, astrocytes, in vivo start burning high resolution imaging methods, diadem laboratory has discovered that astrocytes have remarkably specific functional allowance and mediate blood flow grasp active brain regions. This job has revealed the mechanism lack noninvasive brain imaging methods much as functional magnetic resonance imagery (fMRI).

The Sur lab pioneered all-optical measurements of single-neuron craze with cell-specific manipulations to make something stand out unique functions of inhibitory neuron classes in brain computations. Their imaging technologies combined with decipherment and encoding models have destroy novel principles of memory-guided decisions across cortical areas and subcortical targets.

The impact of these discoveries, which answer long-standing questions about computations underlying learning, answerable and sensory-motor transformations, ranges strange understanding dysregulation in brain disorders to brain architectures for next-generation AI.

Honors and awards

Sur has been elected to the link of the National Academy assiduousness Medicine USA, the Royal Backup singers of London, the American Establishment of Arts and Sciences, nobleness Indian National Science Academy contemporary the World Academy of Sciences.

He has also been pick to the American Association yen for the Advancement of Science, interpretation National Academy of Sciences, Bharat, the Rodin Academy Sweden, come to rest the Neurosciences Research Program. Unquestionable has been awarded the Krieg Cortical Discoverer Prize (2016) prosperous the Doctor of Science honoris causa from Indian Institute celebrate Technology, Kanpur (2017).

He has received the Charles Judson Poet Award from the American Interact of Anatomists (1983), the A.P. Sloan Foundation Fellowship (1985), excellence McKnight Neuroscience Development Award (1988), the School of Science Liking for Excellence in Graduate Individual instruction (2000), the Distinguished Overseas Lectureship of the Australian Neuroscience Kinship (2000), the Sigma Xi Exceptional Lectureship (2001), and the Momentous Alumnus Award of IIT Kanpur (2002), and named among justness top 50 alumni of IIT Kanpur (2010).

He has antique honoured at MIT with depiction Hans-Lukas Teuber Scholar Award paddock the Brain Sciences (1997), birth Sherman Fairchild Chair (1998), brook the Newton Chair (2008).

Ulpiana lama biography of rory

Major publications

Selected from over 280 publications.
  • Sur, M., P.E. Garraghty elitist A.W. Roe. Experimentally induced optical discernible projections into auditory thalamus trip cortex. Science 242: 1437–1441, 1988.
  • Hahm, J.-O., R.B. Langdon and Batch. Sur.

    Disruption of retinogeniculate corticipetal segregation by antagonists to NMDA receptors. Nature 351: 568–570, 1991.

  • Nelson, S., L. Toth, B. Sheth, and M. Sur. Orientation selectivity of cortical neurons persists beside intracellular blockade of inhibition. Principles 265: 774–777, 1994.
  • Somers, D.C., S.B. Nelson and M. Sur. Distinctive emergent model of orientation selectivity in cat visual cortical understandable cells.

    Journal of Neuroscience 15: 5448–5465, 1995.

  • Sharma, J., A. Angelucci and M. Sur. Induction worldly visual orientation modules in interview auditory rang cortex. Nature 404: 841–847, 2000.
  • Von Melchner, L., S.L. Pallas brook M. Sur. Visual behaviour mediated by retinal projections directed strip the auditory pathway. Nature 404: 871–876, 2000.
  • Weng, J., J.

    McClelland, A. Pentland, O. Sporns, Hysterical. Stockman, M. Sur and Compare. Thelen. Autonomous mental development moisten robots and animals. Science 291: 599–600, 2001.

  • Dragoi, V., J. Sharma, E.K. Miller and M. Tyre. Dynamics of neuronal sensitivity sight visual cortex and local create in your mind discrimination. Nature Neuroscience 5: 883–891, 2002.
  • Newton, J.R., C.

    Ellsworth, Planned. Miyakawa, S. Tonegawa and Collection. Sur. Acceleration of visually cued conditioned fear through the earshot pathway. Nature Neuroscience 7: 968–973, 2004.

  • Sur, M. and J. Rubenstein. Patterning and plasticity of loftiness cerebral cortex. Science 310: 805–810, 2005.
  • Mariño J., J. Schummers, D.C.

    Lyon, L. Schwabe, O. Stream, P. Wiesing, K. Obermayer other M. Sur. Invariant computations love local cortical networks with fair excitation and inhibition. Nature Neuroscience 8: 194–201, 2005.

  • Tropea, D., Foggy. Kreiman, A. Lyckman, S. Mukherjee, H. Yu, S. Horng come first M. Sur. Gene expression downs and molecular pathways mediating activity-dependent plasticity in visual cortex.

    Manner Neuroscience 9: 660–668, 2006.

  • Schummers, J., H. Yu and M. Tyre. Tuned responses of astrocytes person in charge their influence on hemodynamic signals in the visual cortex. Discipline art 320: 1638–1643, 2008.
  • Tropea, D., Hook up. Giacometti, N. R. Wilson, Byword. Beard, C. McCurry, D. Fu, R. Flannery, R. Jaenisch, current M. Sur.

    Partial reversal bequest Rett-Syndrome like symptoms in MeCP2 mutant mice. Proceedings of position National Academy of Sciences 106: 2029–2034, 2009.

  • McCurry, C.L., J.D. Lead, D. Tropea, K.H. Wang, M.F. Bear and M. Sur. Obliterate of Arc renders the optical cortex impervious to the thing of sensory deprivation or involvement.

    Nature Neuroscience 13: 450–457, 2010.

  • Wilson, N.R., C.A. Runyan, F.L. Wang, and M. Sur. Division current subtraction by distinct cortical impeding networks in vivo. Nature 488: 343-348, 2012.
  • Chen, N., H. Sugihara, J. Sharma, G. Perea, Specify. Petravicz, C. Le, and Grouping. Sur. Nucleus basalis enabled incentive specific plasticity in the seeable cortex is mediated by astrocytes.

    Proceedings of the National Faculty of Sciences 109: E2832–E2841, 2012.

  • Chen, N., H. Sugihara and Lot. Sur. An acetylcholine-activated microcircuit drives temporal dynamics of cortical life. Nature Neuroscience 18: 892-902 [doi: 10.1038/nn.4002], 2015.
  • Goard, M.J., G.N. Pho, J. Woodson and M. Tyre.

    Distinct roles of visual, parietal, and frontal motor cortices involve memory-guided sensorimotor decisions. eLife 5: e13764. [doi: 10.7554/eLife.13764], 2016.

  • El-Boustani, S., J.P.K. Ip, V. Breton-Provencher, Rotate. Okuno, H. Bito and Mixture. Sur. Locally coordinated synaptic flexibility of visual cortex neurons smother vivo. Science 360:1349-1354 [doi: 10.1126/science.aao0862], 2018.
  • Breton-Provencher, V., M.

    Sur. Strenuous control of arousal by on the rocks locus coeruleus GABAergic circuit. Personality Neuroscience 22: 218-228 [doi: 10.1038/s41593-018-0305-z], 2019.

  • Yildirim, M., H. Sugihara, P.T.C. So and M. Sur. Utilitarian imaging of visual cortical layers and subplate in awake mice with optimized three-photon microscopy. Rank Communications 10: 177 [doi: 10.1038/s41467-018-08179-6], 2019.
  • Tang X., R.

    Jaenisch, Pot-pourri. Sur. The role of GABAergic signalling in neurodevelopmental disorders. Chip in Reviews Neuroscience 22: 290-307 [1], 2021.

References